Peter R Flatt Selected Research

Cholecystokinin (Pancreozymin)

1/2018	Cholecystokinin (CCK) and related adjunct peptide therapies for the treatment of obesity and type 2 diabetes.
11/2015	New perspectives on exploitation of incretin peptides for the treatment of diabetes and related disorders.
12/2013	Enteroendocrine hormone mimetics for the treatment of obesity and diabetes.
8/2013	(pGlu-Gln)-CCK-8[mPEG]: a novel, long-acting, mini-PEGylated cholecystokinin (CCK) agonist that improves metabolic status in dietary-induced diabetes.

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Peter R Flatt Research Topics

Disease

86	Body Weight (Weight, Body) 08/2022 - 09/2004
79	Type 2 Diabetes Mellitus (MODY) 01/2022 - 02/2002
75	Insulin Resistance 08/2022 - 06/2003
63	Obesity 08/2022 - 04/2002
8	Glucose Intolerance 01/2022 - 02/2006
4	Weight Loss (Weight Reduction) 12/2021 - 10/2017
3	Type 1 Diabetes Mellitus (Autoimmune Diabetes) 12/2020 - 02/2004
3	Weight Gain 01/2020 - 12/2006
3	Bone Resorption 10/2016 - 10/2013
3	Necrosis 10/2011 - 11/2005
3	Diabetes Mellitus 01/2010 - 11/2002
2	Polydipsia 11/2016 - 10/2016
2	Hyperphagia (Overeating) 11/2016 - 02/2008
2	Metabolic Syndrome (Dysmetabolic Syndrome X) 08/2016 - 10/2015
2	Cognitive Dysfunction 11/2015 - 09/2010
2	Inflammation (Inflammations) 11/2014 - 11/2014
2	Neoplasms (Cancer) 07/2014 - 05/2008
2	Hyperglycemia 07/2013 - 06/2011
2	Tetraploidy 02/2013 - 06/2011
2	Osteoporosis 09/2010 - 05/2008
2	Hypertrophy 12/2007 - 08/2005
1	Short Bowel Syndrome 01/2021

Drug/Important Bio-Agent (IBA)

98	Glucose (Dextrose)FDA LinkGeneric 08/2022 - 02/2002
72	Insulin (Novolin)FDA Link 08/2022 - 04/2002
61	Peptides (Polypeptides)IBA 08/2022 - 11/2002
35	Glucagon-Like Peptide 1 (GLP 1)IBA 08/2022 - 01/2004
22	Glucagon (Glukagon)FDA Link 08/2022 - 12/2003
17	IncretinsIBA 01/2022 - 12/2003
15	Hormones (Hormone)IBA 01/2018 - 10/2003
14	gastric inhibitory polypeptide receptorIBA 01/2022 - 02/2002
14	Blood Glucose (Blood Sugar)IBA 01/2021 - 09/2006
12	Exenatide (Byetta)FDA Link 08/2022 - 02/2009
12	Triglycerides (Triacylglycerol)IBA 10/2020 - 12/2007
12	EnzymesIBA 01/2018 - 02/2002
11	Hypoglycemic Agents (Hypoglycemics)IBA 01/2022 - 01/2004
10	Streptozocin (Streptozotocin)FDA Link 08/2021 - 06/2011
10	xenin 25 (xenin)IBA 01/2021 - 08/2012
8	Pharmaceutical PreparationsIBA 01/2022 - 12/2006
8	Pro(3)- glucose-dependent insulinotropic polypeptideIBA 07/2012 - 02/2002
7	LipidsIBA 01/2021 - 10/2015
7	Liraglutide FDA Link 12/2020 - 08/2010
6	OxyntomodulinIBA 01/2016 - 12/2010
5	Fatty Acids (Saturated Fatty Acids)IBA 01/2018 - 09/2005
5	Biological ProductsIBA 11/2014 - 08/2003
5	Gastrointestinal Hormones (Hormones, Gastrointestinal)IBA 10/2013 - 09/2005
4	Sitagliptin Phosphate (Januvia)FDA Link 01/2021 - 08/2010
4	Dipeptidyl-Peptidase IV InhibitorsIBA 01/2021 - 09/2006
4	AmidesIBA 12/2020 - 01/2018
4	Gastric Inhibitory Polypeptide (Glucose Dependent Insulinotropic Peptide)IBA 01/2020 - 06/2007
4	Cholecystokinin (Pancreozymin)IBA 01/2018 - 08/2013
4	Antimicrobial Cationic PeptidesIBA 07/2017 - 07/2014
4	monomethoxypolyethylene glycol (MPEG)IBA 08/2013 - 06/2008
3	Glucagon-Like Peptide-1 ReceptorIBA 01/2022 - 04/2007
3	dapagliflozinIBA 12/2020 - 09/2017
3	CholesterolIBA 05/2020 - 04/2016
3	Hydrocortisone (Cortisol)FDA LinkGeneric 01/2020 - 01/2014
3	apelin-13 peptideIBA 01/2020 - 12/2017
3	ApelinIBA 01/2020 - 12/2017
3	Amylases FDA Link 09/2018 - 07/2016
3	(pGlu-Gln)-CCK-8IBA 08/2015 - 01/2013
3	Alanine (L-Alanine)FDA Link 07/2013 - 11/2005
3	PalmitatesIBA 08/2012 - 11/2002
3	Dipeptidyl Peptidase 4 (Dipeptidyl Peptidase IV)IBA 05/2008 - 10/2006
2	Peptide YYIBA 01/2021 - 01/2018
2	CeruletideIBA 01/2021 - 06/2011
2	Cholecystokinin Receptors (Cholecystokinin Receptor)IBA 01/2021 - 01/2013
2	HDL CholesterolIBA 05/2020 - 01/2018
2	LDL CholesterolIBA 01/2018 - 01/2013
2	esculentin steroidIBA 10/2017 - 01/2015
2	Insulin SecretagoguesIBA 04/2016 - 01/2004
2	Glucagon-Like Peptide-1 Receptor AgonistsIBA 12/2015 - 02/2010
2	SecretagoguesIBA 10/2015 - 02/2015
2	Proteins (Proteins, Gene)FDA Link 11/2014 - 07/2013
2	Norepinephrine (Noradrenaline)FDA LinkGeneric 02/2013 - 06/2011
2	CytokinesIBA 10/2011 - 11/2005
2	Arginine (L-Arginine)FDA Link 10/2011 - 11/2005
2	Metformin (Glucophage)FDA LinkGeneric 12/2010 - 10/2006
2	AdiponectinIBA 02/2009 - 06/2008
2	CB1 Cannabinoid Receptor (CB1 Receptor)IBA 06/2008 - 02/2008
2	CannabinoidsIBA 06/2008 - 02/2008
2	AM 251 (AM251)IBA 06/2008 - 02/2008
2	Glycated Hemoglobin (Glycosylated Hemoglobin)IBA 07/2007 - 04/2006
2	glycated insulinIBA 05/2003 - 02/2003
1	Glucagon Receptors (Glucagon Receptor)IBA 08/2022
1	quercitrinIBA 01/2022
1	PhytochemicalsIBA 01/2022
1	semaglutideIBA 01/2022
1	Vasopressins (Vasopressin)IBA 01/2022
1	tirzepatideIBA 01/2022
1	QuercetinIBA 06/2021
1	kaempferolIBA 06/2021
1	Plant ExtractsIBA 01/2021
1	Oxytocin (Pitocin)FDA LinkGeneric 01/2021
1	methionine aminopeptidase 2IBA 01/2021

Therapy/Procedure

33	Therapeutics 01/2022 - 10/2003
10	Intraperitoneal Injections 08/2021 - 02/2006
5	Injections 01/2020 - 09/2005
2	Oral Administration 01/2021 - 06/2019
2	Glycemic Control 10/2017 - 01/2009
1	Bariatric Surgery 12/2021